SIENA FAQ

What type of images can I use in SIENA/SIENAX?

Good quality structural images should be used (T1-weighted, T2-weighted, PD, etc) where the in-plane resolution is better than 2mm (ideally 1mm). The slice thickness is less critical and can be substantially larger than the in-place resolution; The error is almost independent of slice thickness in the range of 1mm to 6mm for 2D acquisitions. Grey/White-matter contrast is not critical to the accuracy of the results as the computations are done using the outer-grey matter surface and the ventricle surface.